An Orally Bioavailable (Mice) Prodrug of Glutathione
نویسندگان
چکیده
منابع مشابه
Identification of GS 4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS 4071.
GS 4071 is a potent carbocyclic transition-state analog inhibitor of influenza virus neuraminidase with activity against both influenza A and B viruses in vitro. GS 4116, the guanidino analog of GS 4071, is a 10-fold more potent inhibitor of influenza virus replication in tissue culture than GS 4071. In this study we determined the oral bioavailabilities of GS 4071, GS 4116, and their respectiv...
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ژورنال
عنوان ژورنال: Antioxidants
سال: 2021
ISSN: 2076-3921
DOI: 10.3390/antiox10060939